How does TB-500 work?
This site's TB-500 profile defines it as a piece of thymosin beta-4, building blocks 17 to 23, with an acetyl group on the front: Ac-LKKTETQ. The idea is that the LKKTET part grabs single units of actin (a protein that shapes cells), the way the parent peptide does. The FDA's 2026 review found no published study giving this fragment to a person in any form, no data on how the body handles it in people, and no reports in the FDA's side-effect database (FAERS) through March 26, 2025. The review also notes that the wound-healing work was done mostly with a version without the acetyl group, or with the full parent peptide. Those results cannot be carried straight over to the piece sold as TB-500. The first registered study of the piece, NCT07487363, is signing people up. This FAQ does not invent a human mechanism from a parent peptide. Full record at /compounds/tb-500.
Studies in people from the compound pages this answer belongs to
Educational use only. This database summarizes published research and is not medical advice. Where a dose appears it is a record of what a trial or clinic ran, or what people describe doing, with its source attached. Nothing here is a recommendation for personal use.
Part of healing and recovery peptides. BPC-157, TB-500, GHK-Cu, and the tissue repair family, including what actually has human data.