Can ipamorelin cause water retention?

This site's ipamorelin studies do not measure water retention or swelling. The one study in people, in 117 patients who had part of their bowel removed, found ipamorelin given by IV drip was well tolerated. They reached a first meal they could keep down a bit sooner than people on a dummy drip (25.3 versus 32.6 hours), but the gap was small enough that it could have been chance. The 1998 paper that first described ipamorelin measured growth hormone release, and how little it raised cortisol and prolactin, in animals, not fluid balance in people. Raising growth hormone is not the same thing as holding water. This FAQ does not invent a side-effect rate the studies do not contain. Full record at /compounds/ipamorelin.

Educational use only. This database summarizes published research and is not medical advice. Where a dose appears it is a record of what a trial or clinic ran, or what people describe doing, with its source attached. Nothing here is a recommendation for personal use.

Part of growth hormone secretagogues. Sermorelin, tesamorelin, ipamorelin, CJC-1295, and the rest of the GHRH and ghrelin receptor family.