What is tesamorelin?
Tesamorelin is a longer-lasting lab version of growth hormone releasing hormone (the body's signal to make growth hormone). It is FDA approved as Egrifta, only to reduce extra deep belly fat in people with HIV who have abnormal fat buildup (lipodystrophy). It works by telling the pituitary gland to release growth hormone, not by supplying growth hormone itself. It is also being studied for thinking and memory in older adults at risk of Alzheimer's disease.
Studies in people from the compound pages this answer belongs to
- Tesamorelin
- Metabolic effects of a growth hormone-releasing factor in patients with HIV 2007 PMID 18057338
- Effects of tesamorelin (TH9507) in HIV-infected patients with excess abdominal fat: a pooled analysis of two multicenter, double-blind placebo-controlled phase 3 trials with safety extension data 2010 PMID 20554713
- Effects of growth hormone-releasing hormone on cognitive function in adults with mild cognitive impairment and healthy older adults: results of a controlled trial 2012 PMID 22869065
Educational use only. This database summarizes published research and is not medical advice. Where a dose appears it is a record of what a trial or clinic ran, or what people describe doing, with its source attached. Nothing here is a recommendation for personal use.
Part of growth hormone secretagogues. Sermorelin, tesamorelin, ipamorelin, CJC-1295, and the rest of the GHRH and ghrelin receptor family.