How does hexarelin work?
Hexarelin is a lab-made peptide, six amino acids long. It switches on the ghrelin receptor (also called the growth hormone secretagogue receptor) to release a burst of growth hormone. This site's profile says the body clears half of it in about 55 minutes. Its molecular weight is 887.0 daltons. In 12 healthy volunteers, hexarelin given into a vein released about twice as much growth hormone as GHRH. Bigger doses gave bigger responses, whether it went into a vein, under the skin, up the nose, or by mouth. When 12 healthy older people used it twice a day for 16 weeks, their growth hormone response dropped by roughly half. The drop was partial and went away four weeks after stopping. A small short study found hexarelin into a vein improved how well the heart pumped in people with heart damage from blocked arteries, but not in people with an enlarged, weak heart, even though growth hormone rose about the same in both. It is not an approved drug. This FAQ does not invent a dose. Full record at /compounds/hexarelin.
Studies in people from the compound pages this answer belongs to
- Hexarelin
- Growth hormone-releasing activity of hexarelin, a new synthetic hexapeptide, after intravenous, subcutaneous, intranasal, and oral administration in man 1994 PMID 8126144
- Does desensitization to hexarelin occur? 1998 PMID 10990150
- GH-independent cardiotropic activities of hexarelin in patients with severe left ventricular dysfunction due to dilated and ischemic cardiomyopathy 2002 PMID 11959048
Educational use only. This database summarizes published research and is not medical advice. Where a dose appears it is a record of what a trial or clinic ran, or what people describe doing, with its source attached. Nothing here is a recommendation for personal use.
Part of growth hormone secretagogues. Sermorelin, tesamorelin, ipamorelin, CJC-1295, and the rest of the GHRH and ghrelin receptor family.