How does ipamorelin work?
It latches onto the ghrelin receptor on the pituitary gland, the same docking spot the hunger hormone ghrelin uses. That sets off a burst of growth hormone. Drugs that copy growth hormone releasing hormone, like sermorelin or CJC-1295, use a different route. That is why the two families are sometimes paired: one makes the bursts bigger, the other makes them more frequent. But no study has tested that pairing in people.
Studies in people from the compound pages this answer belongs to
- Ipamorelin
- Prospective, randomized, controlled, proof-of-concept study of the ghrelin mimetic ipamorelin for the management of postoperative ileus in bowel resection patients 2014 PMID 25331030
- Pharmacokinetic-pharmacodynamic modeling of ipamorelin, a growth hormone releasing peptide, in human volunteers 1999 PMID 10496658
- Safety and Efficacy of Ipamorelin Compared to Placebo for the Recovery of Gastrointestinal Function 2014 NCT01280344
Educational use only. This database summarizes published research and is not medical advice. Where a dose appears it is a record of what a trial or clinic ran, or what people describe doing, with its source attached. Nothing here is a recommendation for personal use.
Part of growth hormone secretagogues. Sermorelin, tesamorelin, ipamorelin, CJC-1295, and the rest of the GHRH and ghrelin receptor family.