How does GHRP-2 work?
GHRP-2, also called pralmorelin, switches on the ghrelin receptor (also called the growth hormone secretagogue receptor) to release a burst of growth hormone from the pituitary gland. This site's profile says the body clears half of it in about 30 to 60 minutes. Its molecular weight is 817.0 daltons. It is approved in Japan as a test of how much growth hormone the pituitary releases. The test was checked in 77 healthy people and 58 people with growth hormone deficiency, using a 100 microgram test dose into a vein, with a cut-off peak of 15 micrograms per litre. In a separate test, a drip of it made seven lean men eat about 36% more when they could eat freely, along with a strong rise in growth hormone. So the appetite effect is smaller, not gone. Those are a diagnostic test and a one-time eating measure, not a treatment approval in the US, UK, Australia, or Canada. This FAQ does not invent a dose. Full record at /compounds/ghrp-2.
Studies in people from the compound pages this answer belongs to
- GHRP-2
- A simple diagnostic test using GH-releasing peptide-2 in adult GH deficiency 2007 PMID 17609397
- Growth hormone releasing peptide-2 (GHRP-2), like ghrelin, increases food intake in healthy men 2005 PMID 15699539
- Treatment effects of intranasal growth hormone releasing peptide-2 in children with short stature 1997 PMID 9390009
Educational use only. This database summarizes published research and is not medical advice. Where a dose appears it is a record of what a trial or clinic ran, or what people describe doing, with its source attached. Nothing here is a recommendation for personal use.
Part of growth hormone secretagogues. Sermorelin, tesamorelin, ipamorelin, CJC-1295, and the rest of the GHRH and ghrelin receptor family.