What are the side effects of MK-677?

In its two year trial in older adults, MK-677 raised fasting blood sugar and worsened insulin resistance while lean mass increased, and strength and physical function did not improve. A separate Phase 2b trial in hip fracture patients was stopped early over a congestive heart failure safety signal, before most of its functional measures showed benefit. Those are the two controlled human trials this site's review found; both surfaced a real safety concern alongside a partial result.

Educational use only. This database summarizes published research and is not medical advice. Where a dose appears it is a record of what a trial or clinic ran, or what people describe doing, with its source attached. Nothing here is a recommendation for personal use.

Part of growth hormone secretagogues. Sermorelin, tesamorelin, ipamorelin, CJC-1295, and the rest of the GHRH and ghrelin receptor family.