Are GLP-1 drugs peptides?

Semaglutide, liraglutide, dulaglutide, and exenatide are peptides. They are chains of amino acids built to resist the fast breakdown that limits the body's own GLP-1 hormone to minutes of action. Tirzepatide and retatrutide are also peptide-based, built to hit more receptors than GLP-1 alone. The whole family comes from exenatide, which was based on a peptide found in Gila monster venom.

Educational use only. This database summarizes published research and is not medical advice. Where a dose appears it is a record of what a trial or clinic ran, or what people describe doing, with its source attached. Nothing here is a recommendation for personal use.

Part of glp-1 and metabolic peptides. Semaglutide, tirzepatide, retatrutide, and the rest of the incretin and glucagon receptor family.