Does retatrutide burn fat?

It caused large average weight loss in studies. That is not the same as a measured fat-burning result in a person. In TRIUMPH-1, with 2,339 people, a company release reported up to 28.3% average weight loss at 80 weeks on 12 milligrams, versus 2.2% on a dummy shot. An earlier study ran 48 weeks in 338 adults, with up to 24.2% loss at 12 milligrams. A small part of an early study found 86% of people on 12 milligrams got their liver fat below 5% at 24 weeks, versus 0% on a dummy shot. The extra glucagon action is thought to make the body burn more energy and more liver fat. That is a theory plus average weight and liver-fat results, not a counted fat-burning rate for one person. Retatrutide is still experimental. A research-chemical vial is not the product used in the studies. This FAQ does not invent a fat-oxidation percentage. Full record at /compounds/retatrutide.

Educational use only. This database summarizes published research and is not medical advice. Where a dose appears it is a record of what a trial or clinic ran, or what people describe doing, with its source attached. Nothing here is a recommendation for personal use.

Part of glp-1 and metabolic peptides. Semaglutide, tirzepatide, retatrutide, and the rest of the incretin and glucagon receptor family.