What was the first GLP-1 drug ever approved?

Exenatide, approved as Byetta. It was based on a peptide called exendin-4, found in Gila monster venom. It started the whole GLP-1 drug family that semaglutide and tirzepatide later built on. Its own studies covered nearly 15,000 people, looking at blood sugar control in type 2 diabetes.

Every FDA-approved compound in the archive, as a list

Educational use only. This database summarizes published research and is not medical advice. Where a dose appears it is a record of what a trial or clinic ran, or what people describe doing, with its source attached. Nothing here is a recommendation for personal use.

Part of glp-1 and metabolic peptides. Semaglutide, tirzepatide, retatrutide, and the rest of the incretin and glucagon receptor family.