Is tirzepatide FDA approved for heart health?
Yes, as of August 2026. A study of more than 13,000 people with type 2 diabetes and existing heart disease found major heart and blood vessel events happened in 12.2% of people on tirzepatide versus 13.1% on dulaglutide, a drug already proven to protect the heart. That met the bar to add heart protection to tirzepatide's label.
Every FDA-approved compound in the archive, as a list
Studies in people from the compound pages this answer belongs to
- Tirzepatide
- Tirzepatide Once Weekly for the Treatment of Obesity (SURMOUNT-1) 2022 PMID 35658024
- Tirzepatide versus Semaglutide Once Weekly in Patients with Type 2 Diabetes (SURPASS-2) 2021 PMID 34170647
- Cardiovascular Outcomes with Tirzepatide versus Dulaglutide in Type 2 Diabetes (SURPASS-CVOT) 2025 PMID 41406444
Educational use only. This database summarizes published research and is not medical advice. Where a dose appears it is a record of what a trial or clinic ran, or what people describe doing, with its source attached. Nothing here is a recommendation for personal use.
Part of glp-1 and metabolic peptides. Semaglutide, tirzepatide, retatrutide, and the rest of the incretin and glucagon receptor family.