Is tirzepatide FDA approved for heart health?

Yes, as of August 2026. A trial of more than 13,000 people with type 2 diabetes and existing heart disease found major cardiovascular events occurred in 12.2% of the tirzepatide group versus 13.1% on dulaglutide, an already proven heart protective drug, meeting the bar to add a cardiovascular indication to tirzepatide's label.

Educational use only. This database summarizes published research and is not medical advice. Where a dose appears it is a record of what a trial or clinic ran, or what people describe doing, with its source attached. Nothing here is a recommendation for personal use.

Part of glp-1 and metabolic peptides. Semaglutide, tirzepatide, retatrutide, and the rest of the incretin and glucagon receptor family.