Does semaglutide expire or need refrigeration?
The FDA approved pens, Ozempic and Wegovy, follow the maker's storage instructions. In general, they stay in the fridge before first use and can be kept at room temperature for a limited time after. For mixed research chemical vials, this site's general mixing advice applies: keep them in the fridge at 2 to 8 degrees Celsius, and expect roughly a 28 day window to use them once mixed, which is how peptide liquids generally behave.
Studies in people from the compound pages this answer belongs to
- Semaglutide
- Semaglutide and Cardiovascular Outcomes in Obesity without Diabetes (SELECT) 2023 PMID 37952131
- Once-Weekly Semaglutide in Adults with Overweight or Obesity (STEP 1) 2021 PMID 33567185
- Efficacy and safety of oral semaglutide 14 mg (flexible dose) in early-stage symptomatic Alzheimer's disease (evoke and evoke+): two phase 3, randomised, placebo-controlled trials 2026 PMID 41865758
Educational use only. This database summarizes published research and is not medical advice. Where a dose appears it is a record of what a trial or clinic ran, or what people describe doing, with its source attached. Nothing here is a recommendation for personal use.
Part of glp-1 and metabolic peptides. Semaglutide, tirzepatide, retatrutide, and the rest of the incretin and glucagon receptor family.