How much semaglutide should I take for weight loss?

This site does not give dosing recommendations, but the approved label is public record. Wegovy is raised step by step up to a 2.4 milligram shot once a week. A higher 7.2 milligram dose was approved in March 2026. That followed a study where people on it lost 18.7% of their weight at 72 weeks, more than on lower doses, but about 23% of that group had odd skin feelings as a side effect. A 25 milligram daily pill was also approved in December 2025. Dosing is a medical decision between you and a prescriber.

Educational use only. This database summarizes published research and is not medical advice. Where a dose appears it is a record of what a trial or clinic ran, or what people describe doing, with its source attached. Nothing here is a recommendation for personal use.

Part of glp-1 and metabolic peptides. Semaglutide, tirzepatide, retatrutide, and the rest of the incretin and glucagon receptor family.