Can retatrutide cause constipation?

This site's retatrutide citations do not report constipation as a counted trial outcome. What they do report is weight (TRIUMPH-1: 2,339 people, up to 28.3% mean weight loss at 80 weeks on 12 milligrams versus 2.2% on placebo; Phase 2: 338 adults, up to 24.2% at 48 weeks) and dysesthesia in about 12.5% on the 12 milligram dose in TRIUMPH-1. Gastrointestinal effects are the class pattern. Constipation is not a published percentage on those finding lines. This FAQ does not invent one. Full record at /compounds/retatrutide.

Educational use only. This database summarizes published research and is not medical advice. Where a dose appears it is a record of what a trial or clinic ran, or what people describe doing, with its source attached. Nothing here is a recommendation for personal use.

Part of glp-1 and metabolic peptides. Semaglutide, tirzepatide, retatrutide, and the rest of the incretin and glucagon receptor family.