Can tirzepatide cause constipation?

This site's tirzepatide citation finding lines do not publish a counted constipation percentage. SURMOUNT-1 reported weight in 2,539 adults at 72 weeks (up to 20.9% mean loss on 15 milligrams versus 3.1% on placebo). SURPASS-2, SURPASS-CVOT, and SURMOUNT-OSA finding lines cover blood sugar, major cardiovascular events, and apnea-hypopnea index. Gastrointestinal effects are the class pattern already discussed on this FAQ for diarrhea. That is not a constipation rate this page can invent. This FAQ does not invent an adverse-event rate the citations do not contain. Full record at /compounds/tirzepatide.

Educational use only. This database summarizes published research and is not medical advice. Where a dose appears it is a record of what a trial or clinic ran, or what people describe doing, with its source attached. Nothing here is a recommendation for personal use.

Part of glp-1 and metabolic peptides. Semaglutide, tirzepatide, retatrutide, and the rest of the incretin and glucagon receptor family.