Is retatrutide safe?

It remains investigational, not FDA approved, so its safety record is still being built through ongoing trials rather than years of real world prescribing. Its Phase 3 trial reported a sensory disturbance, dysesthesia, in about 12.5% of participants on the highest dose, alongside gastrointestinal effects typical of this drug class. That is real trial safety data, not a completed post market safety record the way an approved drug like semaglutide has.

Educational use only. This database summarizes published research and is not medical advice. Where a dose appears it is a record of what a trial or clinic ran, or what people describe doing, with its source attached. Nothing here is a recommendation for personal use.

Part of glp-1 and metabolic peptides. Semaglutide, tirzepatide, retatrutide, and the rest of the incretin and glucagon receptor family.