Is tirzepatide better than semaglutide?

In one direct randomized trial, yes, on the outcomes it measured. Nearly 1,900 people with type 2 diabetes took tirzepatide or semaglutide for about nine months; every tirzepatide dose beat semaglutide's 1 milligram dose on blood sugar control, and the highest tirzepatide dose produced up to 5.5 kilograms more weight loss. One caveat matters: the semaglutide dose used, 1 milligram, is lower than the 2.4 milligram dose approved for weight loss specifically.

Educational use only. This database summarizes published research and is not medical advice. Where a dose appears it is a record of what a trial or clinic ran, or what people describe doing, with its source attached. Nothing here is a recommendation for personal use.

Part of glp-1 and metabolic peptides. Semaglutide, tirzepatide, retatrutide, and the rest of the incretin and glucagon receptor family.