Is liraglutide as effective as semaglutide?

No trial has run a full head to head between the two on weight loss, but liraglutide was the first GLP-1 drug approved specifically for obesity and requires a daily injection rather than weekly, with a shorter half life of about 13 hours versus semaglutide's roughly 7 days. Across the separate trials each drug has been tested in, semaglutide has generally produced larger average weight loss, though that is a comparison across different trials, not one study measuring both directly.

Educational use only. This database summarizes published research and is not medical advice. Where a dose appears it is a record of what a trial or clinic ran, or what people describe doing, with its source attached. Nothing here is a recommendation for personal use.

Part of glp-1 and metabolic peptides. Semaglutide, tirzepatide, retatrutide, and the rest of the incretin and glucagon receptor family.