Is liraglutide as effective as semaglutide?
No study has compared the two head to head on weight loss. Liraglutide was the first GLP-1 drug approved for obesity. It is a daily shot, not weekly, and the body clears half of it in about 13 hours, compared with roughly 7 days for semaglutide. Across the separate studies each drug has been tested in, semaglutide has usually given bigger average weight loss. But that compares different studies, not one study that measured both.
Studies in people from the compound pages this answer belongs to
- Liraglutide
- Liraglutide and Cardiovascular Outcomes in Type 2 Diabetes (LEADER) 2016 PMID 27295427
- A Randomized, Controlled Trial of 3.0 mg of Liraglutide in Weight Management (SCALE Obesity and Prediabetes) 2015 PMID 26132939
- Efficacy of Liraglutide for Weight Loss Among Patients With Type 2 Diabetes: The SCALE Diabetes Randomized Clinical Trial 2015 PMID 26284720
Educational use only. This database summarizes published research and is not medical advice. Where a dose appears it is a record of what a trial or clinic ran, or what people describe doing, with its source attached. Nothing here is a recommendation for personal use.
Part of glp-1 and metabolic peptides. Semaglutide, tirzepatide, retatrutide, and the rest of the incretin and glucagon receptor family.